Search results for "centenarians' offspring"

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Centenarians' offspring as a model of healthy aging: a reappraisal of the data on Italian subjects and a comprehensive overview.

2016

Within the scenario of an increasing life expectancy worldwide it is mandatory to identify determinants of healthy aging. Centenarian offspring (CO) is one of the most informative model to identify trajectories of healthy aging and their determinants (genetic and environmental), being representative of elderly in their 70th whose lifestyle can be still modified to attain a better health. This study is the first comprehensive investigation of the health status of 267 CO (mean age: 70.2 years) and adopts the innovative approach of comparing CO with 107 age‐matched offspring of non‐long‐lived parents (hereafter indicated as NCO controls), recruited according to strict inclusion demographic cri…

MaleGerontologyAgingmedicine.medical_specialtyWaistOffspringage-related diseases; aging/longevity; centenarians' offspring; health status; inflammagingHealth StatusLongevityhealth statuPsychological intervention030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineage-related diseases030502 gerontologycentenarians’ offspringEpidemiologyaging/longevity centenarians’ offspring health status inflammaging age‐related diseasesmedicineHumanscentenarians' offspring10. No inequalityAgedSettore MED/04 - Patologia Generaleage-related diseasemedicine.diagnostic_testbusiness.industryCase-control studyCell Biology3. Good healthItalyCase-Control StudiesLife expectancyinflammagingFemaleCentenarian0305 other medical scienceLipid profilebusinessResearch Paperaging/longevityDemography
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Does the longevity of one or both parents influence the health status of their offspring?

2013

According to the findings of some recent studies, the centenarians' offspring appear to represent a promising model for research on longevity and healthy aging. This study compares the health status and the functional status of three groups of subjects: 1. individuals with two long-lived parents (one of whom centenarian), 2. individuals with only one long-lived (centenarian) parent, and 3. individuals with no long-lived parents. The goal is to verify whether the centenarians' offspring display any advantage over the offspring of both non-long-lived parents and to evaluate whether the longevity of the non centenarian parent provides a further advantage. A total of 374 subjects (mean age appr…

MaleParentsGerontologyAgingActivities of daily livingOffspringmedia_common.quotation_subjectLongevityHEALTH STATUSFAMILIAL LONGEVITYBiochemistryLife ExpectancyEndocrinologyRisk FactorsSurveys and QuestionnairesActivities of Daily LivingGeneticsHumansMedicineHealthy agingGeriatric AssessmentMolecular BiologySurvival analysisAgedDemographymedia_commonSettore MED/04 - Patologia GeneraleAged 80 and overCENTENARIANS' OFFSPRINGbusiness.industryLongevityCensusesRegression analysisHealth Status DisparitiesCell BiologyHEALTHY AGINGSurvival AnalysisItalySocioeconomic FactorsFUNCTIONAL STATUSLife expectancyAdult ChildrenRegression AnalysisFemaleCentenarianbusinessHealthy aging Familial longevity Centenarians' offspring Health status Functional status.Experimental Gerontology
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